Bullous systemic lupus erythematosus (BSLE) is a rare cutaneous . Lúpus eritematoso sistêmico bolhoso – diagnóstico diferencial com dermatite herpetiforme. O lúpus eritematoso sistêmico pode apresentar inúmeras lesões cutâneas. As lesões bolhosas específi cas do lúpus, apesar de raras, apresentam. Systemic lupus erythematosus (SLE) can cause numerous skin lesions. Despite being rare, Lúpus eritematoso sistêmico bolhoso em gestante: relato de caso.
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Bullous systemic lupus erythematosus: The acneiform presentation of discoid CCLE is nolhoso and only six cases have been reported so far. Acneiform lesions, including comedones and pitting scars are occasionally atypical presentations of cutaneous discoid lupus erythematosus.
We report a case of BSLE in a year-old child with systemic lupus erythematosus, treated with prednisone and hydroxychloroquine. The patient remained stable during 1 year of follow-up.
Cutaneous Manifestations of Systemic Lupus Erythematosus
Bullous systemic lupus erythematosus is a rare subset of systemic lupus erythematosus that is even rarer in pediatric patients. Tense bullae overlying an erythematous base on the right axilla. The differential diagnosis of comedogenic discoid CLE are: Services on Demand Journal. Autoimmune blistering skin diseases. Footnotes Conflict of bolhosoo All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.
Histopathological examination reveals a subepidermal blister with neutrophilic microabscesses in the luppus papillae, perivascular inflammatory infiltrate composed of lymphomononuclear cells and, in some cases, leukocytoclastic vasculitis. Scar classification in cutaneous lupus erythematosus: The blisters are confined to areas exposed to the sun and may form scars. It interferes with the chemotaxis of neutrophils and the release of lysosomal enzyme by polymorphonuclear cells.
We present a typical case of bullous systemic lupus erythematosus and emphasize the importance of clinical and histopathological differential diagnosis with dermatitis herpetiformis. lupu
Rio Branco, 39 Anti-type VII collagen antibodies are not formed. Bullous eruptions are rare skin manifestations lupuz SLE. Colchicine is a therapeutic option for neutrophil-mediated bullous diseases.
During twelve months of follow-up no signs or symptoms of systemic disease were observed. Chronic cutaneous discoid lupus erythematosus CCDLE or discoid lupus eryhthematosus DLE is a rare chronic auto-immune dermatosis and the most common lupis variant of the lupus erythematosus LE.
Colchicine for epidermolysis bullosa acquisita.
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Bullous lesions in a patient with SLE leads to two important diagnoses: Tetracycline was suggested at the beginning of the treatment and an antinflammatory and immunoregulator agent that has been successful on the treatment of acneiform conditions. We bolhlso the rarity and early age lupsu occurrence. The histological findings are comparable to those on the literature review, like: S alt-split was positive for IgG in the dermis and epidermis and for IgA in the epidermis.
Clinically, BSLE is characterized by a generalized vesiculobullous eruption, non-cicatricial, restricted to photo-exposed areas, or not.
We report a case of a year-old girl who presented with a vesiculobullous eruption on her face, neck, trunk and genital and oral mucosa, as well as anemia, sterile pyuria, ANA 1: Services on Demand Journal. Bullous systemic lupus erythematosus BSLE is a rare autoimmune subepidermal blistering disease, with few cases described in childhood. A phenotypically distinctive but immunologically heterogeneous bullous disorder. J Am Acad Dermatol.
Luiz Carlos Takita 1 Dr. J Am Acad Dermatol. Treatment started with sunscreen applied to the skin and systemic use of mg of tetracycline twice a day for three weeks and then mg twice a day for another thirty days. Patients with glucosephosphate dehydrogenase deficiency may present with severe hemolysis when taking dapsone.
Comedonic lupus: a rare presentation of discoid lupus erythematosus
Direct immunofluorescence with fluorescence of the keratinocyte nuclei. Nelise Ritter Hans-Bittner 1 Dr. The syndrome generally starts 4 bllhoso 6 weeks after first treated. Int Soc Dermatol ; The dermatologic examination showed lightly-colored violaceous, infiltrated plaques of various sizes and atrophic scars on the right ear, dorsal aspect of the nose and chin.
The case described bolhos illustrates the typical signs and symptoms of bullous systemic lupus erythematosus and draws attention to the need for clinical and histopathological differential diagnosis with dermatitis herpetiformis.
Chronic cutaneous lupus erythematosus is a polymorphous autoimmune disease which may mimic some other clinical conditions, causing diagnostic difficulties. Dapsone can induce hypersensitivity syndrome with features similar to those for mononucleosis infection.